Cognition or higher brain activity is sometimes seen as a phenomenon greater than the sum of its parts. This viewpoint however is largely dependent on the state of the art of experimental techniques that endeavor to characterize morphology and its association to function. Retinal ganglion cells are readily accessible for this work and we discuss recent advances in computational techniques in identifying novel parameters that describe structural attributes possibly associated with specific function. These parameters are based on calculating wavelet gradients (...) from cell images followed by the extraction of meaningful measures including 2nd wavelet moment, entropy of orientation, and curvature. For the three cell types analyzed, the mean 2nd wavelet moment, which relates to the field of influence of the dendritic-tree segments was significantly different. cells had the highest mean 2nd wavelet moment, followed by the and cells (134 ± 22, 93 ± 19 and 63 ± 12, respectively). There was no significant difference between cells for entropy of orientation, indicating no class with a preferential orientation of their dendritic tree. Curvature provided similar results to the 2nd wavelet moment with cells having the highest curvature followed by and the cells (mean ± SD: 161 ± 15; 134 ± 22; 121 ± 15). Our feature space analysis also indicated a difference between these cell types. No difference was found between the and cell types and their physiological counterparts the Y and X cells based on wavelet analysis. Both the X and Y cells can be divided into two subtypes, the ON- and OFF-center cells based on the stratification level of the dendritic tree within the retina. Using 2nd wavelet moment, a difference in their morphological attributes, not reported previously, was noted for these subtypes. The 2nd wavelet moment and curvature are further discussed with respect to explaining regularity of spacing and coverage associated with retinal ganglion cell mosaics. (shrink)

IntroductionTranscranial magnetic stimulation is a consolidated procedure for the treatment of depression, with several meta-analyses demonstrating its efficacy. Theta-burst stimulation is a modification of TMS with similar efficacy and shorter session duration. The geriatric population has many comorbidities and a high prevalence of depression, but few clinical trials are conducted specifically for this age group. TBS could be an option in this population, offering the advantages of few side effects and no pharmacological interactions. Therefore, our aim is to investigate the (...) efficacy of TBS in geriatric depression.Clinical trial registration[https://clinicaltrials.gov/ct2/], identifier [NCT04842929]. (shrink)

A full separation theorem for the derivable rules of intuitionistic linear logic without bounds, 0 and exponentials is proved. Several structural consequences of this theorem for subreducts of (commutative) residuated lattices are obtained. The theorem is then extended to the logic LR+ and its proof is extended to obtain the finite embeddability property for the class of square increasing residuated lattices.

The logic RM and its basic fragments (always with implication) are considered here as entire consequence relations, rather than as sets of theorems. A new observation made here is that the disjunction of RM is definable in terms of its other positive propositional connectives, unlike that of R. The basic fragments of RM therefore fall naturally into two classes, according to whether disjunction is or is not definable. In the equivalent quasivariety semantics of these fragments, which consist of subreducts of (...) Sugihara algebras, this corresponds to a distinction between strong and weak congruence properties. The distinction is explored here. A result of Avron is used to provide a local deduction-detachment theorem for the fragments without disjunction. Together with results of Sobociski, Parks and Meyer (which concern theorems only), this leads to axiomatizations of these entire fragments — not merely their theorems. These axiomatizations then form the basis of a proof that all of the basic fragments of RM with implication are finitely axiomatized consequence relations. (shrink)

Overzicht van de rationalistische traditie in de filosofie van de kunst sinds Kant door een hoogleraar aan de Leuvense universiteit.

On principle, there are no language classifications which are right or wrong, but only classifications which are more or less useful or useless. This statement at the beginning of my paper is intended to indicate the teleological perspective in which I want to view the more general problems involved in the classification of African languages. I shall discuss these within a framework which I derive from the four main components of any language classification, namely:1.the aims and objectives of language classification,2.the (...) basic units to be classified,3.the criteria of classification,4.the models of language classification. (shrink)

Incidental fndings of potential medical signifcance are seen in approximately 5-8 percent of asymptomatic subjects and 16 percent of symptomatic subjects participating in large computed tomography colonography studies, with the incidence varying further by CT acquisition technique. While most CTC research programs have a well-defned plan to detect and disclose IFs, such plans are largely communicated only verbally. Written consent documents should also inform subjects of how IFs of potential medical signifcance will be detected and reported in CTC research studies.

In recent years evidence has emerged of the considerable influence of Scotist metaphysics on the Reformed scholasticism of the seventeenth century. One of the figures often named in connection with this Scotist revival is Samuel Rutherford (1600–61), who was one of the most important Scottish theologians of the seventeenth century. Focussing on Rutherford’s maximalist doctrine of providence, this article demonstrates his profound debt to key Scotist philosophical devices. In structuring these concepts, however, it is demonstrated that Rutherford is influenced not (...) so much by Scotus directly but rather much more by the modified Scotism of Thomas Bradwardine, the fourteenth-century Augustinian theologian. In particular, Bradwardine is revealed as the key influence on Rutherford’s modal theory and his sophisticated account of divine concourse. The paper concludes by arguing that Bradwardine’s influence on Rutherford suggests the need to take a broader view of the late medieval influence on Reformed scholasticism than is currently the case. (shrink)

Philosophie et sciences: voila un theme difficile, central, de notre temps, ou il est necessairement question de son sens. C'est ce sens qu'interrogent, d'une facon a la fois historique et problematique, les essais du present volume. J. Merleau-Ponty questionne les rapports entre sciences et vulgarisation scientifique. J. Ladriere pose le probleme de La normativite de la pensee scientifique. J. Lambert met en evidence le probleme du Livre de la Nature chez Galilee et Kepler. P. Kerszberg confronte les structures internes de (...) la philosophie critique kantienne et de la theorie de la relativite sur la question cosmologique. M. Richir analyse L'illusion transcendantale dans la theorie cantorienne des ensembles. B. d'Espagnat et G. Hottois evoquent le problemes des rapports difficiles, aujourd'hui, entre science et philosophie. (shrink)